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dc.contributor.authorSur, Unzile
dc.contributor.authorErkekoglu, Pinar
dc.contributor.authorBulus, Ayse Derya
dc.contributor.authorAndiran, Nesibe
dc.contributor.authorKocer-Gumusel, Belma
dc.date.accessioned2021-01-25T07:21:31Z
dc.date.available2021-01-25T07:21:31Z
dc.date.issued2019-11-01
dc.identifier.other31354016
dc.identifier.urihttp://hdl.handle.net/20.500.12591/501
dc.description.abstractIn this study, we aimed to investigate whether bisphenol A (BPA) and di-(2-ethylhexyl) phthalate (DEHP) exposure have any association with Hashimoto's thyroiditis (HT) and its biomarkers and to determine whether oxidative stress biomarkers and trace element levels showed any alterations in children with HT. We found that superoxide dismutase and glutathione peroxidase activities are lower in HT group from control (24% and 46%, respectively,  < 0.05). Zinc levels were significantly lower in HT group vs. control. In addition, the levels of mono-(2-ethylhexyl) phthalate (MEHP) which is the primary metabolite for DEHP, were markedly higher in HT group compared to control ( < 0.05). A negative correlation was observed between urinary BPA levels and fT4. In children with HT, oxidant/antioxidant balance is changed and these differences may be related by EDC exposure, the importance of which should be elucidated with further studies.en_US
dc.language.isoengen_US
dc.publisherEzcacılık Fakültesien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectBisphenol Aen_US
dc.subjectHashimoto’s thyroiditisen_US
dc.subjectdi-(2-ethylhexyl) phthalateen_US
dc.subjectiodineen_US
dc.subjectoxidative stressen_US
dc.subjectseleniumen_US
dc.subjectthyroid hormonesen_US
dc.subjectzincen_US
dc.titleOxidative stress markers, trace elements, and endocrine disrupting chemicals in children with Hashimoto's thyroiditis.en_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.contributor.departmentFarmasötik Teknolojien_US


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