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Selenium, selenoproteins and Hashimoto's thyroiditis
(Ezcacılık Fakültesi, 2020-03-01)selenium is a trace element that has important functions within the body. it is suggested that there is a link between selenium levels and thyroid functions since the enzymes involved in the synthesis of thyroid hormones ... -
The beneficial effect of clove essential oil and its major component, eugenol, on erectile function in diabetic rats.
(Ezcacılık Fakültesi, 2020-07-01)Diabetic men are at a higher risk of erectile dysfunction (ED). A tropical plant, clove (Syn. Eugenia caryophyllata, Caryophyllus aromaticus L., Syzygium aromaticum (L.) Merr. & L.M. Perry) from the Myrtaceae family has ... -
Polymeric Nanoparticle Versus Liposome Formulations: Comparative Physicochemical and Metabolomic Studies as L-Carnitine Delivery Systems.
(Ezcacılık Fakültesi, 2020-11-06)L-Carnitine has attracted much more attention especially in the treatment of crucial diseases such as diabetes, regional slimming, and obesity because of its metabolic activities. However, because of its short half-life, ... -
Seseli petraeum M. Bieb. (Apiaceae) Significantly Inhibited Cellular Growth of A549 Lung Cancer Cells through G0/G1 Cell Cycle Arrest.
(Ezcacılık Fakültesi, 2020-12-31)Seseli L. is an important genus of the Apiaceae family, with a large number of aromatic species. It is used in traditional medicine extensively, but there is quite limited information on their phytochemicals and biological ... -
Oxidative Stress Parameters, Selenium Levels, DNA Damage, and Phthalate Levels in Plastic Workers.
(Ezcacılık Fakültesi, 2019-07-17)Di(2-ethylhexyl)phthalate (DEHP) is the most widely used phthalate. DEHP is highly used in PVC floorings and PVC windows and carpeting. The objective of this study was to determine sex hormone levels, oxidative stress ... -
Capacitive properties of novel N-alkyl substituted poly(3,6-dithienyl-9H-carbazole)s as redox electrode materials and their symmetric micro-supercapacitor applications
(Elsevier Ltd, 2018)Herein, we present a comparative study about charge storage performances of novel N-alkyl substituted poly(3,6-dithienylcarbazole)-based electrodes for supercapacitor applications. The poly(3,6-dithienylcarbazole) derivatives, ... -
Regioselective N–alkylation of 2– (3,4–dimethoxyphenyl)imidazo[4,5–b] and [4,5–c]pyridine oxide derivatives: Synthesis and structure elucidation by NMR
(Elsevier B.V., 2019)Imidazopyridines can exist in several tautomeric forms such as benzimidazole or purine condensed systems. Regioselectivities were determined for N-alkylations of 2-(3,4-dimethoxyphenyl)- imidazopyridines and their 4 and ... -
The effects of amniotic fluid and foetal cord blood cotinine concentrations on pregnancy complications and the anthropometric measurements of newborns
(Taylor and Francis Ltd, 2019)Our objective was determining the effects of amniotic fluid (AF) and fetal cord blood (FCB) cotinine concentrations on pregnancy complications and the anthropometric measurements in the newborns whose mothers underwent ... -
Prenatal bisphenol a and phthalate exposure are risk factors for male reproductive system development and cord blood sex hormone levels
(Elsevier Inc., 2019)Bisphenol A (BPA) and phthalates can adversely affect the fetal development. However, observational studies on the effects of these chemicals on fetal male reproductive system are still limited. A hundred of umbilical cord ... -
Lead and Mercury Levels in Preterm Infants Before and After Blood Transfusions
(Humana Press Inc., 2019)Very low birth weight (VLBW) infants usually receive packed red blood cell unit (pRBC) transfusions. Heavy metal transfer via pRBCs is not widely discussed before. This study aimed to determine pre-/post-transfusion ... -
Oxidative stress markers, trace elements, and endocrine disrupting chemicals in children with Hashimoto’s thyroiditis
(Taylor and Francis Ltd, 2019)In this study, we aimed to investigate whether bisphenol A (BPA) and di-(2-ethylhexyl) phthalate (DEHP) exposure have any association with Hashimoto’s thyroiditis (HT) and its biomarkers and to determine whether oxidative ... -
Effects of prenatal and lactational bisphenol a and/or di(2-ethylhexyl) phthalate exposure on male reproductive system
(Taylor and Francis Ltd., 2020)Bisphenol A (BPA) and phthalates are abundantly used endocrine disrupting chemicals (EDCs). The aim of this study was to evaluate the effects of single and combined exposures to BPA and/or di(2-ethylhexyl) phthalate (DEHP) ... -
Assessment of oxidant-antioxidant status alterations with tumor biomarkers and reproductive system hormones in uterine MYOMAS
(Elsevier Ireland Ltd, 2018)Objectives: Uterine myomas (UM) are responsible for significant morbidity and have adverse effects on quality of life in women. Reactive oxygen species (ROS) and antioxidant enzymes (AOE), as well as sex steroids play ... -
Urinary bisphenol-A levels in children with type 1 diabetes mellitus
(Walter de Gruyter GmbH, 2018)Bisphenol-A (BPA) is one of the most abundantly produced chemicals globally. Concerns have been raised about BPA's possible role in the pathogenesis of type 1 diabetes mellitus (T1DM). The main aim of the current study was ... -
Bisphenol A and phthalate levels in adolescents with polycystic ovary syndrome
(Taylor and Francis Ltd, 2019)Endocrine disruptors have been proposed in the etiology of polycystic ovary syndrome (PCOS) as they have the potency to interfere with hormone-sensitivity systems. The aim of this study was to evaluate the levels of bisphenol ... -
Evaluation of the antioxidant potency of Seseli L. species (apiaceae) [Seseli L. Türlerinin (apiaceae) antioksidan potansiyellerinin değerlendirilmesi]
(Turkish Pharmacists Association, 2020)Objectives: In the present study, the antioxidant potency of ethyl acetate (AcOEt) and methanol (MeOH) extracts from the aerial parts of Seseli L. species was investigated for the first time. Materials and Methods: Seseli ... -
Assessment of in vitro antigenotoxic effect of nigella sativa oil [Nigella sativa yağının in vitro antigenotoksik etkisinin değerlendirilmesi]
(Turkish Pharmacists Association, 2020)Objectives: Cyclophosphamide (CP) is an alkylating agent widely used as an antineoplastic and immunosuppressive agent. The genotoxicity of CP has been studied in a variety of in vivo and in vitro systems and is routinely ... -
The cardiopulmonary effects of the calcitonin gene-related peptide family [Kalsitonin-geni ile ilişkili peptit ailesinin kardiyopulmoner etkileri]
(Turkish Pharmacists Association, 2020)Cardiopulmonary diseases are very common among the population. They are high-cost diseases and there are still no definitive treatments. The roles of members of the calcitonin-gene related-peptide (CGRP) family in treating ... -
Synthesis, molecular modelling and biological activity of some pyridazinone derivatives as selective human monoamine oxidase-B inhibitors
(Springer, 2020)Background: Since brain neurotransmitter levels are associated with the pathology of various neurodegenerative diseases like Parkinson and Alzheimer, monoamineoxidase (MAO) plays a critical role in balancing these ... -
The effects of different bisphenol derivatives on oxidative stress, DNA damage and DNA repair in RWPE-1 cells: A comparative study
(John Wiley and Sons Ltd, 2020)Bisphenol A (BPA) is a well-known endocrine disruptor and it is widely used mainly in the plastics industry. Due to recent reports on its possible impact on health (particularly on the male reproductive system), bisphenol ...
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