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Lokman Hekim University Institutional Repository is a growing collection of Lokman Hekim University’s research that includes peer-reviewed articles, technical reports, working papers, theses and more.

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Myeloid maturation potentiates STAT3-mediated atypical IFN-gamma signaling and upregulation of PD-1 ligands in AML and MDS

Yoyen-Ermis, Didem; Tunali, Gurcan; Tavukcuoglu, Ece; Horzum, Utku; Ozkazanc, Didem; Sutlu, Tolga; Buyukasik, Yahya; Esendagli, Gunes (Tıp Fakültesi, 2019-08-12)

Interferon (IFN)-gamma is the major mediator of anti-tumor immune responses; nevertheless, cancer cells use intrigue strategies to alter IFN-gamma signaling and avoid elimination. Understanding the immune regulatory ...

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Myeloid maturation potentiates STAT3-mediated atypical IFN-gamma signaling and upregulation of PD-1 ligands in AML and MDS