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dc.contributor.authorTakci, Sahin
dc.contributor.authorAsci, Ali
dc.contributor.authorErkekoglu, Pinar
dc.contributor.authorYiğit, Sule
dc.contributor.authorKocer-Gumusel, Belma
dc.contributor.authorYurdakök, Murat
dc.date.accessioned2021-01-19T11:07:12Z
dc.date.available2021-01-19T11:07:12Z
dc.date.issued2019-04-01
dc.identifier.other30066064
dc.identifier.urihttp://hdl.handle.net/20.500.12591/486
dc.description.abstractVery low birth weight (VLBW) infants usually receive packed red blood cell unit (pRBC) transfusions. Heavy metal transfer via pRBCs is not widely discussed before. This study aimed to determine pre-/post-transfusion erythrocyte lead and mercury levels in infants and to correlate these levels to heavy metal concentrations in pRBCs. VLBW infants (n = 80), needing pRBC transfusion for the first time, were enrolled. Erythrocyte heavy metal levels were determined in pre-/post-transfusion blood samples and also in pRBC units. Mean lead and mercury levels in the pRBCs were found to be 16.3 ± 10.8 and 3.75 ± 3.23 μg/L, respectively. Of the infants, 69.7% received lead above reference dose. Erythrocyte lead levels increased significantly after transfusions (10.6 ± 10.3 vs. 13 ± 8.5, p < 0.05) with significant correlated to amount of lead within pRBCs (r = 0.28). Mean pre-/post-transfusion erythrocyte mercury levels were 3.28 ± 3.08 and 3.5 ± 2.83 μg/L, respectively (p > 0.05). There was a significant correlation between mean difference of mercury levels after transfusion and amount of mercury delivered by pRBCs (r = 0.28). Infants can be subject to high levels of lead and mercury through pRBC transfusions.en_US
dc.language.isoengen_US
dc.publisherEzcacılık Fakültesien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectBlood transfusionen_US
dc.subjectLeaden_US
dc.subjectMercuryen_US
dc.subjectNeonateen_US
dc.subjectPrematurityen_US
dc.titleLead and Mercury Levels in Preterm Infants Before and After Blood Transfusions.en_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.contributor.departmentFarmasötik Teknolojien_US


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