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dc.contributor.authorUnal, Emine
dc.contributor.authorKaradag, Ayse Serap
dc.contributor.authorSikar Akturk, Aysun
dc.contributor.authorDizen Namdar, Nazli
dc.contributor.authorKelekci, Kiymet Handan
dc.contributor.authorAksoy, Berna
dc.contributor.authorOzlu, Emin
dc.contributor.authorBaykal, Leyla
dc.contributor.authorKaraman, Goksun
dc.contributor.authorSaricaoglu, Hayriye
dc.contributor.authorZindanci, Ilkin
dc.contributor.authorBalta, Ilknur
dc.contributor.authorTuran, Cagri
dc.contributor.authorCan Kuru, Burce
dc.description.abstractBackground Acne vulgaris is a chronic inflammatory skin disease that affects the pilosebaceous unit. Although it is considered to be a skin-limited disease, different clinical studies have recently been published in which the disease is accompanied by systemic symptoms. In this study, systemic comorbidities accompanying acne vulgaris and the relationship between existing comorbidities and disease severity are investigated. Methods This prospective multicenter study was conducted by the Turkish Society of Dermatology Acne Study Group. Twelve dermatology clinics and 14 clinicians throughout Turkey participated in the study. A structured physician-administered questionnaire was used to collect patient demographics, clinical findings, and lifestyle data. Physicians recorded each participant's medical history, including current and past comorbidities, duration of any comorbidity, smoking, and drinking. Body mass index (BMI) was calculated. Results There were 3022 patients in the adolescent acne group and 897 in the control group. The incidence of nonmigraine headache in adolescents with acne was significantly higher than in the nonacne group (P = 0.019). There were 680 patients in the postadolescent acne group and 545 in the control group. In the postadolescent group, incidence of metabolic disease was lower than the control group (P = 0.003). In the postadolescent group, premenstrual syndrome (P < 0.001) and PCOS (P = 0.007) were more common than the control group. Conclusions In this study, we observed that acne vulgaris does not cause systemic comorbidities. There is also a need for new studies involving a large number of patients to illuminate systemic diseases accompanying acne vulgaris.en_US
dc.publisherTıp Fakültesien_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.titleAnalysis of 3702 patients with acne vulgaris and concomitant comorbidities in Turkey: a multi-centered, prospective, controlled study.en_US
dc.contributor.departmentDahili Tıp Bilimlerien_US

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