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dc.contributor.authorAltıntaş, Bernas
dc.contributor.authorÖzkalaycı, Flora
dc.contributor.authorÇinier, Göksel
dc.contributor.authorKaya, İlyas
dc.contributor.authorAktan, Adem
dc.contributor.authorKüp, Ayhan
dc.contributor.authorOnuk, Raşit
dc.contributor.authorÖzcan, Sevgi
dc.contributor.authorUslu, Abdulkadir
dc.contributor.authorAkyüz, Abdurrahman
dc.contributor.authorAtıcı, Adem
dc.contributor.authorEkinci, Selim
dc.contributor.authorAkın, Halil
dc.contributor.authorYılmaz, Mehmet Fatih
dc.contributor.authorKoç, Şahbender
dc.contributor.authorTanık, Veysel Ozan
dc.contributor.authorHarbalıoğlu, Hazar
dc.contributor.authorBarman, Hasan Ali
dc.contributor.authorAfşin, Abdülmecit
dc.contributor.authorGümüşdağ, Ayça
dc.contributor.authorAlibaşiç, Hayrudin
dc.contributor.authorKarabağ, Yavuz
dc.contributor.authorCap, Murat
dc.contributor.authorBaysal, Erkan
dc.contributor.authorTanboğa, İbrahim Halil
dc.description.abstractAim: Current literature lacks a definitive threshold of idiopathic premature ventricular complex (PVC) burden for predicting cardiomyopathy (CMP). The main objective of the present study was to evaluate relationship between the PVC burden and left ventricular ejection fraction (LVEF). Method: This multicenter, cross-sectional study included 341 consecutive patients with more than 1,000 idiopathic PVC in 24 hr of Holter monitoring admitted to the cardiology clinics between January 2019 and May 2019 in the nineteen different centers. The primary outcome was the LVEF measured during the echocardiographic examination. Result: Overall, the median age was 50 (38-60) and 139 (49.4%) were female. Percentage of median PVC burden was 9% (IQR: 4%-17.4%). Median LVEF was found 60% (55-65). We used proportional odds logistic regression method to examine the relationship between continuous LVEF and candidate predictors. Increase in PVC burden (%) (regression coefficient (RE) -0.644 and 95% CI -1.063, -0.225, p < .001), PVC QRS duration (RE-0.191 and 95% CI -0.529, 0.148, p = .049), and age (RE-0.249 and 95% CI -0.442, -0.056, p = .018) were associated with decrease in LVEF. This inverse relationship between the PVC burden and LVEF become more prominent when PVC burden was above 5%. A nomogram developed to estimate the individual risk for decrease in LVEF. Conclusion: Our study showed that increase in PVC burden %, age, and PVC QRS duration were independently associated with decrease in LVEF in patients with idiopathic PVC. Also, inverse relationship between PVC burden and LVEF was observed in lower PVC burden than previously known.en_US
dc.publisherTıp Fakültesien_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.subjectleft ventricular ejection fractionen_US
dc.subjectpremature ventricular complexesen_US
dc.titleThe effect of idiopathic premature ventricular complexes on left ventricular ejection fraction.en_US
dc.contributor.departmentTemel Tıp Bilimlerien_US

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