Medial Meniscus Scaffold Implantation in Combination with Concentrated Bone Marrow Aspirate Injection: Minimum 3-Year Follow-up
Date
2020Author
Akkaya, Mustafa
Simsek, Mehmet Emin
Gursoy, Safa
Cay, Nurdan
Bozkurt, Murat
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The objective of this study is to show the short-term clinical and
radiological outcomes of concentrated bone marrow aspirate (CBMA)
injection administered in combination with medial meniscus scaffold
implantation. Twenty-three patients who received intra-articular CBMA
injection in combination with polyurethane-based medial meniscus
scaffold implantation were evaluated within the scope of this study. The
International Knee Documentation Committee (IKDC) questionnaire and the
Knee injury and Osteoarthritis Outcome Score (KOOS) were used to
evaluate the results, and the visual analog scale was used to assess the
pain scores. Magnetic resonance imaging (MRI) scans were obtained in the
preoperative period and at postoperative months 1, 12, 24, and 36 to
assess the scaffold position as well as chondral degeneration/damage in
a comparative manner. MRI assessment was performed by using the modified
Outerbridge scale for cartilage and the Genovese scoring system for the
meniscal implant. Twenty-three patients who were included in the study
were evaluated for a mean follow-up period of 38.3 months. Patients
exhibited statistically significant improvement according to all scoring
data from the preoperative period until the follow-up period. The mean
postoperative extrusion at year 3 was 2.39 mm (distribution 2.30-2.56
mm). There was no significant difference in the distribution of the
degree of chondral damage between the preoperative and 3-year follow-up
periods. Four patients did not show any improvement nor had lower scores
according to the assessment. Medial meniscus scaffold implantation
combined with intra-articular CBMA injection resulted in a significant
improvement in all functions and pain scores as well as a statistically
significant clinical improvement in IKDC and KOOS values in the
short-term follow-up. The Level of evidence for this study is IV.
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