Evaluation of the Antioxidant Potency of Seseli L. Species (Apiaceae)
Date
2020Author
Onder, Alev and Cinar, Ahsen Sevde and Sarialtin, Sezen Yilmaz and Izgi,
Mehmet Necat and Coban, Tulay
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Objectives: In the present study, the antioxidant potency of ethyl
acetate (AcOEt) and methanol (MeOH) extracts from the aerial parts of
Seseli L. species was investigated for the first time.
Materials and Methods: Seseli species L. such as Seseli andronakii
Woronow ex Schischk., S. campestre Besser, S. corymbosum Boiss. \&
Heldr., S. gummiferum subsp. gummiferum Pall. ex Sm., S. hartvigii
Parolly \& Nordt, S. libanotis (L.) W.Koch, S. petraeum M.Bieb., S.
peucedanoides (M.Bieb.) Koso-Pol., S. resinosum Freyn \& Sint., and S.
tortuosum L. growing in Turkey were collected and evaluated for their
antioxidant capacity by using 1.1-diphenyl-2-picrylhydrazyl (DPPH)
radical scavenging and lipid peroxidation (LPO) inhibition methods.
Results: The highest activities as a scavenger of DPPH radicals were
found in the AcOEt extracts of S. peucedanoides (M.Bieb.) Koso-Pol
(IC50=0.49 mg/mL), and S. libanotis (IC50=0.75 mg/mL); alpha-tocopherol
was used as a positive control. On the other hand, in the LPO assay, the
highest activities were determined in AcOEt and MeOH extracts (at 5
mg/mL) of S. tortuosum and S. libanotis (84-94\%).
Conclusion: This report gives important information about the
antioxidant capacity of Seseli L. species. This research on antioxidant
capacity proves that the use of some species used in Eastern Anatolia
(in salads) is correct. With this screening study performed in Seseli L.
species growing in Turkey, in the future, it is planned to isolate
antioxidant compounds from the most active strains of Seseli L.
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