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Bimodal Effects of P2Y Antagonism on Matrix Metalloproteinase-Associated Contractile Dysfunction in İnsulin-Resistant Mammalian Heart.
(Tıp Fakültesi, 2021-07-16)
The matrix metalloproteinases (MMPs) contribute to matrix remodeling in diabetes via tissue degradation; however, their contributions can be different depending on the pathology. For instance, MMPs are elevated in acute ...
The role of labile Zn and Zn-transporters in the pathophysiology of mitochondria dysfunction in cardiomyocytes.
(Tıp Fakültesi, 2021-02-01)
An important energy supplier of cardiomyocytes is mitochondria, similar to other mammalian cells. Studies have demonstrated that any defect in the normal processes controlled by mitochondria can lead to abnormal ROS ...